2026

Elevated translocator protein in skull bone marrow is linked to human chronic pain (opens in a new tab)

Mehrbod Mohammadian, Nikos Efthimiou, Katherin Gabriel, Ludovica Brusaferri, Joya Cooper-Hohn, Minhae Kim, Jennifer P Murphy, Zeynab Alshelh, Grace Grmek, Jack H Schnieders, Courtney A Chane, Thomas G Carmichael, Danika Yang, Julia J Schubert, Federico E Turkheimer, Rafael A Cazuza, Peter M Grace, Ciprian Catana, Steven M Stufflebeam, Robert R Edwards, Vitaly Napadow, Kimberly Sullivan, Matthias Nahrendorf, Theodore J Price, Jodi M Gilman, Marco L Loggia

Sci Transl Med. 2026 Sep 2;18(865):eaed8729. doi: 10.1126/scitranslmed.aed8729. Epub 2026 Sep 2.

DOI: 10.1126/scitranslmed.aed8729 (opens in a new tab)

PMID: 42685155 (opens in a new tab)

Neuroinflammation in knee osteoarthritis is accompanied by functional reorganization of the S1 cortical knee representation (opens in a new tab)

Silvia Fanton, Minhae Kim, Zeynab Alshelh, Ludovica Brusaferri, Erin J Morrissey, Angel Torrado-Carvajal, Grace Grmek, Courtney Chane, Margaret A Wargo, Jennifer Murphy, Robert R Edwards, Nikos Efthimiou, Mehrbod Mohammadian, Ekim Luo, Vitaly Napadow, Marco L Loggia

Brain Behav Immun. 2026 Aug 23;139:106972. doi: 10.1016/j.bbi.2026.106972. Online ahead of print.

DOI: 10.1016/j.bbi.2026.106972 (opens in a new tab)

PMID: 42633817 (opens in a new tab)

Anterior midcingulate cortex activity during pain catastrophizing predicts and sequentially tracks reduction in pain interference after cognitive behavioral therapy in fibromyalgia (opens in a new tab)

Jeungchan Lee, Asimina Lazaridou, Myrella Paschali, Alessandra Anzolin, Arvina Grahl, Dan-Mikael Ellingsen, Marco L Loggia, Ajay D Wasan, Robert R Edwards, Vitaly Napadow

Pain. 2026 Jul 1;167(7):1593-1602. doi: 10.1097/j.pain.0000000000003957. Epub 2026 Apr 1.

DOI: 10.1097/j.pain.0000000000003957 (opens in a new tab)

PMID: 41925517 (opens in a new tab)

Mechano responsiveness of neuroimmune cross-talk in bone and joints: A narrative review with implications for force-based manipulations (opens in a new tab)

Karl J Lewis, Jennifer Bent, Per Gunnar Brolinson, Damian Keter, Ellen Lumpkin, Jan Mundo, Vitaly Napadow, William R Reed, Brent S Russell, Simon Y Tang, Mary F Barbe

Musculoskelet Sci Pract. 2026 Apr;82:103470. doi: 10.1016/j.msksp.2025.103470. Epub 2026 Jan 31.

DOI: 10.1016/j.msksp.2025.103470 (opens in a new tab)

PMID: 41620320 (opens in a new tab)

Brain levels of the neurotransmitter γ-aminobutyric acid are reduced in people with HIV-related neuropathic pain (opens in a new tab)

Angelica Sandström, Minhae Kim, Akila Weerasekera, Yang Lin, Kelly Castro-Blanco, Aarushi Tandon, Jennifer Murphy, Keenan Byrne, Zeynab Alshelh, Angel Torrado-Carvajal, Burel R Goodin, Richard Ahern, Christine Marx, Jason Kilts, Rajesh T Gandhi, Vitaly Napadow, Robert R Edwards, Lauren Pollak, Shibani S Mukerji, Marco L Loggia, Eva-Maria Ratai

Pain. 2026 Jan 1;167(1):e8-e17. doi: 10.1097/j.pain.0000000000003794. Epub 2025 Sep 3.

DOI: 10.1097/j.pain.0000000000003794 (opens in a new tab)

PMID: 40893017 (opens in a new tab)

2025

Evidence for a role of skull bone marrow in human chronic pain as revealed by TSPO PET imaging (opens in a new tab)

Mehrbod Mohammadian, Nikos Efthimiou, Ludovica Brusaferri, Joya Cooper-Hohn, Minhae Kim, Jennifer P Murphy, Zeynab Alshelh, Grace Grmek, Jack H Schnieders, Courtney A Chane, Thomas G Carmichael, Danika Yang, Ciprian Catana, Steven M Stufflebeam, Robert R Edwards, Vitaly Napadow, Kimberly Sullivan, Matthias Nahrendorf, Jodi M Gilman, Marco L Loggia

medRxiv [Preprint]. 2025 Jul 21:2025.07.19.25331817. doi: 10.1101/2025.07.19.25331817.

DOI: 10.1101/2025.07.19.25331817 (opens in a new tab)

PMID: 41551382 (opens in a new tab)

Artificial Intelligence in Acupuncture: Recommendations from the Society for Acupuncture Research Special Interest Group Artificial Intelligence and Digital Health (opens in a new tab)

Claudia M Witt, Casey Murphy, Sandro Graca, Christa Angell, Megan K Gale, Chun Sing Lam, Vitaly Napadow, Ryosuke Izawa, Sungwon Woo, Suzanna M Zick, Ye-Seul Lee

J Integr Complement Med. 2025 Dec;31(12):1012-1020. doi: 10.1177/27683605251389440. Epub 2025 Oct 24.

DOI: 10.1177/27683605251389440 (opens in a new tab)

PMID: 41182266 (opens in a new tab)

Investigating the potential of minocycline in reducing brain inflammation in chronic low back pain: a randomized, placebo-controlled mechanistic clinical trial (opens in a new tab)

Mehrbod Mohammadian, Erin J Morrissey, Paulina C Knight, Ludovica Brusaferri, Minhae Kim, Nikolaos Efthimiou, Jennifer P Murphy, Zeynab Alshelh, Grace Grmek, Jack H Schnieders, Courtney A Chane, Angelica Sandström, Ciprian Catana, Jodi M Gilman, Joseph J Locascio, Robert R Edwards, Yi Zhang, Vitaly Napadow, Marco L Loggia

Pain. 2025 Apr 9;166(9):2044-2053. doi: 10.1097/j.pain.0000000000003543.

DOI: 10.1097/j.pain.0000000000003543 (opens in a new tab)

PMID: 40839604 (opens in a new tab)

Baseline characteristics of participants in the Biomarkers for Evaluating Spine Treatments clinical trial: a sequential multiple assignment randomized trial for chronic low back pain† (opens in a new tab)

Bryce Rowland, Kelly S Barth, Kevin M Bell, Amber K Brooks, Andrea L Chadwick, Annika Cleven, Robert W Hurley, Sean Mackey, Kushang V Patel, Sara R Piva, Michael J Schneider, Fatima Al-Kadhi, Bernice Asante-Nketiah, Sarah Bagaason, Anna Batorsky, Jeffrey J Borckardt, Anton E Bowden, Timothy S Carey, Joel Castellanos, Lucy Chen, Brooke Chidgey, Diane Dalton, Jonathan S Dufour, Jaclyn L Eberting, Seth M Eller, Aaron J Fields, Julie M Fritz, Amber Fu, Inam Ghulamhussain, Rachel West Goolsby, Carol M Greco, Sarah Grim, Cameron A Gunn, Lindsay Hanes, Richard E Harris, Steven E Harte, Afton L Hassett, Kinsey Helton, Anna Hoffmeyer, Anastasia Ivanova, Sara Jones Berkeley, Chelsea Kaplan, Kelley M Kidwell, Gregory G Knapik, Michael R Kosorok, Gregorij Kurillo, David Li, Remy Lobo, Joseph Long, Jeffrey C Lotz, Prasath Mageswaran, Sharmila Majumdar, Jianren Mao, William S Marras, Lance M McCracken, Micah McCumber, Samuel A McLean, Miranda McMillan, Wolf Mehling, Rafael Mendoza, Ulrike H Mitchell, Vitaly Napadow, Conor O'Neill, Sydnee Pearson, Scott Peltier, Sean D Rundell, Sonja Ryser, Andrew Schrepf, Emily Schulze, John Sperger, Nam Vo, Mark S Wallace, Abigail M Wampler, Ajay D Wasan, Tristan E Weaver, Kenneth A Weber, Lauren Wilcox, David A Williams, Leslie Wilson, Jacqueline E Woo, Fadel Zeidan, Beibo Zhao, Brianna Zhou, Kevin J Anstrom, Daniel J Clauw, Gwendolyn A Sowa, Matthew C Mauck

Pain Med. 2025 Nov 1;26(11):758-772. doi: 10.1093/pm/pnaf073.

DOI: 10.1093/pm/pnaf073 (opens in a new tab)

PMID: 40794568 (opens in a new tab)

Evaluating brain mechanisms of combined vagus nerve stimulation and mindfulness training for migraine: A randomized 2 × 2 factorial clinical trial protocol (opens in a new tab)

Zev Schuman-Olivier, Frances Marin, Lillian D Kinder, Michael Datko, Kassandra Round, Sarasa Tohyama, Ronald G Garcia, Randy L Hirschtick, Robert R Edwards, Rebecca Erwin Wells, Hsinlin T Cheng, Riccardo Barbieri, Nouchine Hadjikhani, Marco L Loggia, Ted J Kaptchuk, Timothy T Houle, Bruce R Rosen, Vitaly Napadow

Contemp Clin Trials. 2025 Jul;154:107947. doi: 10.1016/j.cct.2025.107947. Epub 2025 May 21.

DOI: 10.1016/j.cct.2025.107947 (opens in a new tab)

PMID: 40409681 (opens in a new tab)

Brain inflammation and its predictive value for post-operative pain in total knee arthroplasty patients (opens in a new tab)

Zeynab Alshelh, Ludovica Brusaferri, Erin Janas Morrissey, Angel Torrado-Carvajal, Minhae Kim, Oluwaseun Akeju, Grace Grmek, Courtney Chane, Jennifer Murphy, Andrew Schrepf, Richard E Harris, Young-Min Kwon, Hany Bedair, John Siliski, Antonia F Chen, Christopher Melnic, Mohamed Jarraya, Vitaly Napadow, Mattia Veronese, Lucia Maccioni, Robert R Edwards, Nikos Efthimiou, Mehrbod Mohammadian, Ekim Luo, Lauren E Pollak, Ciprian Catana, Nicola Toschi, Marco L Loggia

Brain Behav Immun. 2025 Aug;128:703-712. doi: 10.1016/j.bbi.2025.05.008. Epub 2025 May 10.

DOI: 10.1016/j.bbi.2025.05.008 (opens in a new tab)

PMID: 40354834 (opens in a new tab)

Investigating the potential of minocycline in reducing brain inflammation in chronic low back pain: a randomized, placebo-controlled mechanistic clinical trial (opens in a new tab)

Mehrbod Mohammadian, Erin J Morrissey, Paulina C Knight, Ludovica Brusaferri, Minhae Kim, Nikolaos Efthimiou, Jennifer P Murphy, Zeynab Alshelh, Grace Grmek, Jack H Schnieders, Courtney A Chane, Angelica Sandström, Ciprian Catana, Jodi M Gilman, Joseph J Locascio, Robert R Edwards, Yi Zhang, Vitaly Napadow, Marco L Loggia

Pain. 2025 Apr 9:10.1097/j.pain.0000000000003543. doi: 10.1097/j.pain.0000000000003543. Online ahead of print.

DOI: 10.1097/j.pain.0000000000003543 (opens in a new tab)

PMID: 40228108 (opens in a new tab)

The design and rationale of the Biomarkers for Evaluating Spine Treatments trial: a sequential multiple assignment randomized trial (opens in a new tab)

Matthew C Mauck, Kelly S Barth, Kevin M Bell, Amber K Brooks, Andrea L Chadwick, Cameron A Gunn, Robert W Hurley, Anastasia Ivanova, Sara R Piva, Michael J Schneider, Jeannie F Bailey, Sarah Bagaason, Anna Batorsky, Jeffrey J Borckardt, Anton E Bowden, Timothy S Carey, Joel Castellanos, Lucy Chen, Brooke Chidgey, Diane Dalton, Jonathan S Dufour, Aaron J Fields, Julie M Fritz, Rachel West Goolsby, Carol M Greco, Richard E Harris, Steven Harte, Afton L Hassett, Anna Hoffmeyer, Sara Jones Berkeley, Chelsea Kaplan, Kelley M Kidwell, Gregory G Knapik, Michael R Kosorok, Gregorij Kurillo, Remy Lobo, Jeffrey C Lotz, Sean Mackey, Prasath Mageswaran, Sharmila Majumdar, Jianren Mao, William S Marras, Micah McCumber, Samuel A McLean, Wolf Mehling, Ulrike H Mitchell, Vitaly J Napadow, Conor O'Neill, Kushang V Patel, Scott Peltier, Matthew Psioda, Bryce Rowland, Sean D Rundell, Andrew Schrepf, John Sperger, Nam Vo, Mark S Wallace, Ajay D Wasan, Tristan E Weaver, Kenneth A Weber, David A Williams, Leslie Wilson, Fadel Zeidan, Beibo Zhao, Kevin J Anstrom, Daniel J Clauw, Gwendolyn A Sowa

Pain Med. 2025 Sep 1;26(9):538-553. doi: 10.1093/pm/pnaf032.

DOI: 10.1093/pm/pnaf032 (opens in a new tab)

PMID: 40205455 (opens in a new tab)

Childhood abuse and health outcomes in patients with fibromyalgia: a cross-sectional exploratory study of the moderating effects of pain catastrophizing and mindfulness (opens in a new tab)

Jolin B Yamin, Samantha M Meints, Bethany D Pester, Madelyn Crago, Lauren Papianou, Asimina Lazaridou, Myrella Paschali, Vitaly Napadow, Robert R Edwards

BMC Musculoskelet Disord. 2025 Feb 25;26(1):195. doi: 10.1186/s12891-025-08449-7.

DOI: 10.1186/s12891-025-08449-7 (opens in a new tab)

PMID: 40001098 (opens in a new tab)

Trigeminal nerve microstructure is linked with neuroinflammation and brainstem activity in migraine (opens in a new tab)

Sarasa Tohyama, Michael Datko, Ludovica Brusaferri, Lillian D Kinder, Jack H Schnieders, Mackenzie Hyman, Alison M Goldstein, Melaina D Gilbert, Hope Housman, Vi Le, Kassandra Round, Frances Marin, Megan R Heffernan, Ronald G Garcia, Randy L Gollub, Robert R Edwards, Bruce R Rosen, Nouchine Hadjikhani, Hsinlin T Cheng, Zev Schuman-Olivier, Marco L Loggia, Vitaly Napadow

Brain. 2025 Jul 7;148(7):2551-2562. doi: 10.1093/brain/awaf029.

DOI: 10.1093/brain/awaf029 (opens in a new tab)

PMID: 39873385 (opens in a new tab)

Neural regulation of pain anticipation is associated with mindful behavior change in patients with anxiety or depression: A pilot study (opens in a new tab)

Michael Datko, Jacqueline Lutz, Richa Gawande, Alexandra Comeau, Jenny Gan, My Ngoc To, Gaelle Desbordes, Todd Griswold, Jean King, Eric Loucks, Vitaly Napadow, Zev Schuman-Olivier

Psychiatry Res Neuroimaging. 2025 Mar;347:111941. doi: 10.1016/j.pscychresns.2024.111941. Epub 2024 Dec 11.

DOI: 10.1016/j.pscychresns.2024.111941 (opens in a new tab)

PMID: 39752812 (opens in a new tab)

Altered parasympathetic outflow and central sensitization response to continuous pain in cyclic vomiting syndrome: a functional magnetic resonance imaging study (opens in a new tab)

Andrew Bolender, Rowan Staley, Ronald G Garcia, Riccardo Barbieri, Ovidiu Andronesi, Shahar Castel, Andrea Thurler, Vitaly Napadow, Braden Kuo, Roberta Sclocco

Am J Physiol Gastrointest Liver Physiol. 2025 Feb 1;328(2):G125-G135. doi: 10.1152/ajpgi.00011.2024. Epub 2024 Nov 15.

DOI: 10.1152/ajpgi.00011.2024 (opens in a new tab)

PMID: 39545877 (opens in a new tab)

2024

Protocol for a Pilot Study on the Neurocardiac Mechanism of an Interoceptive Compassion-Based Heart-Smile Training for Depression (opens in a new tab)

Eunmi Kim, Diane Joss, Frannie Marin, Alessandra Anzolin, Richa Gawande, Alexandra Comeau, Seneca Ellis, Clare Bumpus, B Rael Cahn, Misan W D Kim, Vitaly Napadow, Zev Schuman-Olivier

Glob Adv Integr Med Health. 2024 Nov 3;13:27536130241299389. doi: 10.1177/27536130241299389. eCollection 2024 Jan-Dec.

DOI: 10.1177/27536130241299389 (opens in a new tab)

PMID: 39498312 (opens in a new tab)

Statistical modeling of acute and chronic pain patient-reported outcomes obtained from ecological momentary assessment (opens in a new tab)

Andrew Leroux, Ciprian Crainiceanu, Scott Zeger, Margaret Taub, Briha Ansari, Tor D Wager, Emine Bayman, Christopher Coffey, Carl Langefeld, Robert McCarthy, Alex Tsodikov, Chad Brummet, Daniel J Clauw, Robert R Edwards, Martin A Lindquist, ; A2CPS Consortium

Pain. 2024 Sep 1;165(9):1955-1965. doi: 10.1097/j.pain.0000000000003214. Epub 2024 May 7.

DOI: 10.1097/j.pain.0000000000003214 (opens in a new tab)

PMID: 38718196 (opens in a new tab)

Neuroimmune activation and increased brain aging in chronic pain patients after the COVID-19 pandemic onset (opens in a new tab)

Ludovica Brusaferri, Zeynab Alshelh, Jack H Schnieders, Angelica Sandström, Mehrbod Mohammadian, Erin J Morrissey, Minhae Kim, Courtney A Chane, Grace C Grmek, Jennifer P Murphy, Julia Bialobrzewski, Alexa DiPietro, Julie Klinke, Yi Zhang, Angel Torrado-Carvajal, Nathaniel Mercaldo, Oluwaseun Akeju, Ona Wu, Bruce R Rosen, Vitaly Napadow, Nouchine Hadjikhani, Marco L Loggia

Brain Behav Immun. 2024 Feb;116:259-266. doi: 10.1016/j.bbi.2023.12.016. Epub 2023 Dec 9.

DOI: 10.1016/j.bbi.2023.12.016 (opens in a new tab)

PMID: 38081435 (opens in a new tab)

[ 11 C]-PBR28 positron emission tomography signal as an imaging marker of joint inflammation in knee osteoarthritis (opens in a new tab)

Angelica Sandström, Angel Torrado-Carvajal, Erin J Morrissey, Minhae Kim, Zeynab Alshelh, Yehui Zhu, Matthew D Li, Connie Y Chang, Mohamed Jarraya, Oluwaseun Akeju, Andrew Schrepf, Richard E Harris, Young-Min Kwon, Hany Bedair, Antonia F Chen, Nathaniel D Mercaldo, Norman Kettner, Vitaly Napadow, Nicola Toschi, Robert R Edwards, Marco L Loggia

Pain. 2024 May 1;165(5):1121-1130. doi: 10.1097/j.pain.0000000000003114. Epub 2023 Nov 28.

DOI: 10.1097/j.pain.0000000000003114 (opens in a new tab)

PMID: 38015622 (opens in a new tab)

Thalamic neurometabolite alterations in chronic low back pain: a common phenomenon across musculoskeletal pain conditions? (opens in a new tab)

Akila Weerasekera, Paulina C Knight, Zeynab Alshelh, Erin J Morrissey, Minhae Kim, Yi Zhang, Vitaly Napadow, Alessandra Anzolin, Angel Torrado-Carvajal, Robert R Edwards, Eva-Maria Ratai, Marco L Loggia

Pain. 2024 Jan 1;165(1):126-134. doi: 10.1097/j.pain.0000000000003002. Epub 2023 Aug 11.

DOI: 10.1097/j.pain.0000000000003002 (opens in a new tab)

PMID: 37578456 (opens in a new tab)

2023

Large-scale momentary brain co-activation patterns are associated with hyperalgesia and mediate focal neurochemistry and cross-network functional connectivity in fibromyalgia (opens in a new tab)

Ishtiaq Mawla, Zirui Huang, Chelsea M Kaplan, Eric Ichesco, Noah Waller, Tony E Larkin, Helge J Zöllner, Richard A E Edden, Steven E Harte, Daniel J Clauw, George A Mashour, Vitaly Napadow, Richard E Harris

Pain. 2023 Dec 1;164(12):2737-2748. doi: 10.1097/j.pain.0000000000002973. Epub 2023 Sep 26.

DOI: 10.1097/j.pain.0000000000002973 (opens in a new tab)

PMID: 37751539 (opens in a new tab)

Brain-to-brain mechanisms underlying pain empathy and social modulation of pain in the patient-clinician interaction (opens in a new tab)

Dan-Mikael Ellingsen, Kylie Isenburg, Changjin Jung, Jeungchan Lee, Jessica Gerber, Ishtiaq Mawla, Roberta Sclocco, Arvina Grahl, Alessandra Anzolin, Robert R Edwards, John M Kelley, Irving Kirsch, Ted J Kaptchuk, Vitaly Napadow

Proc Natl Acad Sci U S A. 2023 Jun 27;120(26):e2212910120. doi: 10.1073/pnas.2212910120. Epub 2023 Jun 20.

DOI: 10.1073/pnas.2212910120 (opens in a new tab)

PMID: 37339198 (opens in a new tab)

Attenuated facial movement in depressed women is associated with symptom severity, and nucleus accumbens functional connectivity (opens in a new tab)

Changjin Jung, Jieun Kim, Sunyoung Choi, Young Kyung Seo, Ki-Sun Park, Youngeun Choi, Sung Min Choi, Ojin Kwon, Youngkyu Song, Jooyeon Kim, Gyunggoo Cho, Chaejoon Cheong, Vitaly Napadow, In Chul Jung, Hyungjun Kim

Neuroimage Clin. 2023;38:103380. doi: 10.1016/j.nicl.2023.103380. Epub 2023 Mar 16.

DOI: 10.1016/j.nicl.2023.103380 (opens in a new tab)

PMID: 36989853 (opens in a new tab)

Hypothetical model ignores many important pathophysiologic mechanisms in fibromyalgia (opens in a new tab)

Daniel J Clauw, Ernest H S Choy, Vitaly Napadow, Anushka Soni, Kevin F Boehnke, Bruce Naliboff, Afton L Hassett, Anne Arewasikporn, Andrew Schrepf, Chelsea M Kaplan, David Williams, Neil Basu, Rachel S Bergmans, Richard E Harris, Steven E Harte, Andrea Chadwick, Gary J Macfarlane

Nat Rev Rheumatol. 2023 May;19(5):321. doi: 10.1038/s41584-023-00951-3.

DOI: 10.1038/s41584-023-00951-3 (opens in a new tab)

PMID: 36964334 (opens in a new tab)

Assessing the potential anti-neuroinflammatory effect of minocycline in chronic low back pain: Protocol for a randomized, double-blind, placebo-controlled trial (opens in a new tab)

Erin J Morrissey, Zeynab Alshelh, Paulina C Knight, Atreyi Saha, Minhae Kim, Angel Torrado-Carvajal, Yi Zhang, Robert R Edwards, Chelsea Pike, Joseph J Locascio, Vitaly Napadow, Marco L Loggia

Contemp Clin Trials. 2023 Mar;126:107087. doi: 10.1016/j.cct.2023.107087. Epub 2023 Jan 16.

DOI: 10.1016/j.cct.2023.107087 (opens in a new tab)

PMID: 36657520 (opens in a new tab)

2022

Increased insula response to interoceptive attention following mindfulness training is associated with increased body trusting among patients with depression (opens in a new tab)

Michael Datko, Jacqueline Lutz, Richa Gawande, Alexandra Comeau, My Ngoc To, Tenzin Desel, Jenny Gan, Gaelle Desbordes, Vitaly Napadow, Zev Schuman-Olivier

Psychiatry Res Neuroimaging. 2022 Dec;327:111559. doi: 10.1016/j.pscychresns.2022.111559. Epub 2022 Oct 22.

DOI: 10.1016/j.pscychresns.2022.111559 (opens in a new tab)

PMID: 36308976 (opens in a new tab)

Study protocol for a phase II, double-blind, randomised controlled trial of cannabidiol (CBD) compared with placebo for reduction of brain neuroinflammation in adults with chronic low back pain (opens in a new tab)

Chelsea K Pike, Minhae Kim, Kristina Schnitzer, Nathaniel Mercaldo, Robert Edwards, Vitaly Napadow, Yi Zhang, Erin Janas Morrissey, Zeynab Alshelh, A Eden Evins, Marco L Loggia, Jodi M Gilman

BMJ Open. 2022 Sep 19;12(9):e063613. doi: 10.1136/bmjopen-2022-063613.

DOI: 10.1136/bmjopen-2022-063613 (opens in a new tab)

PMID: 36123113 (opens in a new tab)

Percutaneous electric nerve field stimulation alters cortical thickness in a pilot study of veterans with fibromyalgia (opens in a new tab)

Anna Woodbury, Lisa C Krishnamurthy, Anastasia Bohsali, Venkatagiri Krishnamurthy, Jeremy L Smith, Melat Gebre, Kari Tyler, Mark Vernon, Bruce Crosson, Jerry P Kalangara, Vitaly Napadow, Jason W Allen, Daniel Harper

Neurobiol Pain. 2022 May 17;12:100093. doi: 10.1016/j.ynpai.2022.100093. eCollection 2022 Aug-Dec.

DOI: 10.1016/j.ynpai.2022.100093 (opens in a new tab)

PMID: 35733704 (opens in a new tab)

Cine gastric MRI reveals altered Gut-Brain Axis in Functional Dyspepsia: gastric motility is linked with brainstem-cortical fMRI connectivity (opens in a new tab)

Roberta Sclocco, Harrison Fisher, Rowan Staley, Kyungsun Han, April Mendez, Andrew Bolender, Jaume Coll-Font, Norman W Kettner, Christopher Nguyen, Braden Kuo, Vitaly Napadow

Neurogastroenterol Motil. 2022 Oct;34(10):e14396. doi: 10.1111/nmo.14396. Epub 2022 May 13.

DOI: 10.1111/nmo.14396 (opens in a new tab)

PMID: 35560690 (opens in a new tab)

Patient-clinician brain concordance underlies causal dynamics in nonverbal communication and negative affective expressivity (opens in a new tab)

Dan-Mikael Ellingsen, Andrea Duggento, Kylie Isenburg, Changjin Jung, Jeungchan Lee, Jessica Gerber, Ishtiaq Mawla, Roberta Sclocco, Robert R Edwards, John M Kelley, Irving Kirsch, Ted J Kaptchuk, Nicola Toschi, Vitaly Napadow

Transl Psychiatry. 2022 Jan 28;12(1):44. doi: 10.1038/s41398-022-01810-7.

DOI: 10.1038/s41398-022-01810-7 (opens in a new tab)

PMID: 35091536 (opens in a new tab)

Neuroimmune signatures in chronic low back pain subtypes (opens in a new tab)

Zeynab Alshelh, Ludovica Brusaferri, Atreyi Saha, Erin Morrissey, Paulina Knight, Minhae Kim, Yi Zhang, Jacob M Hooker, Daniel Albrecht, Angel Torrado-Carvajal, Michael S Placzek, Oluwaseun Akeju, Julie Price, Robert R Edwards, Jeungchan Lee, Roberta Sclocco, Ciprian Catana, Vitaly Napadow, Marco L Loggia

Brain. 2022 Apr 29;145(3):1098-1110. doi: 10.1093/brain/awab336.

DOI: 10.1093/brain/awab336 (opens in a new tab)

PMID: 34528069 (opens in a new tab)

2021

3D magnetic resonance spectroscopic imaging reveals links between brain metabolites and multidimensional pain features in fibromyalgia (opens in a new tab)

Jeungchan Lee, Ovidiu C Andronesi, Angel Torrado-Carvajal, Eva-Maria Ratai, Marco L Loggia, Akila Weerasekera, Michael P Berry, Dan-Mikael Ellingsen, Laura Isaro, Asimina Lazaridou, Myrella Paschali, Arvina Grahl, Ajay D Wasan, Robert R Edwards, Vitaly Napadow

Eur J Pain. 2021 Oct;25(9):2050-2064. doi: 10.1002/ejp.1820. Epub 2021 Jun 22.

DOI: 10.1002/ejp.1820 (opens in a new tab)

PMID: 34102707 (opens in a new tab)

International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020) (opens in a new tab)

Adam D Farmer, Adam Strzelczyk, Alessandra Finisguerra, Alexander V Gourine, Alireza Gharabaghi, Alkomiet Hasan, Andreas M Burger, Andrés M Jaramillo, Ann Mertens, Arshad Majid, Bart Verkuil, Bashar W Badran, Carlos Ventura-Bort, Charly Gaul, Christian Beste, Christopher M Warren, Daniel S Quintana, Dorothea Hämmerer, Elena Freri, Eleni Frangos, Eleonora Tobaldini, Eugenijus Kaniusas, Felix Rosenow, Fioravante Capone, Fivos Panetsos, Gareth L Ackland, Gaurav Kaithwas, Georgia H O'Leary, Hannah Genheimer, Heidi I L Jacobs, Ilse Van Diest, Jean Schoenen, Jessica Redgrave, Jiliang Fang, Jim Deuchars, Jozsef C Széles, Julian F Thayer, Kaushik More, Kristl Vonck, Laura Steenbergen, Lauro C Vianna, Lisa M McTeague, Mareike Ludwig, Maria G Veldhuizen, Marijke De Couck, Marina Casazza, Marius Keute, Marom Bikson, Marta Andreatta, Martina D'Agostini, Mathias Weymar, Matthew Betts, Matthias Prigge, Michael Kaess, Michael Roden, Michelle Thai, Nathaniel M Schuster, Nicola Montano, Niels Hansen, Nils B Kroemer, Peijing Rong, Rico Fischer, Robert H Howland, Roberta Sclocco, Roberta Sellaro, Ronald G Garcia, Sebastian Bauer, Sofiya Gancheva, Stavros Stavrakis, Stefan Kampusch, Susan A Deuchars, Sven Wehner, Sylvain Laborde, Taras Usichenko, Thomas Polak, Tino Zaehle, Uirassu Borges, Vanessa Teckentrup, Vera K Jandackova, Vitaly Napadow, Julian Koenig

Front Hum Neurosci. 2021 Mar 23;14:568051. doi: 10.3389/fnhum.2020.568051. eCollection 2020.

DOI: 10.3389/fnhum.2020.568051 (opens in a new tab)

PMID: 33854421 (opens in a new tab)

Acupuncture Research in Animal Models: Rationale, Needling Methods and the Urgent Need for a Standards for Reporting Interventions in Clinical Trials of Acupuncture-Standards for Reporting Interventions in Acupuncture Using Animal Models Adaptation (opens in a new tab)

Ari Ojeda Ocampo Moré, Richard E Harris, Vitaly Napadow, Lisa Taylor-Swanson, Peter M Wayne, Claudia M Witt, Lixing Lao

J Altern Complement Med. 2021 Mar;27(3):193-197. doi: 10.1089/acm.2021.0076.

DOI: 10.1089/acm.2021.0076 (opens in a new tab)

PMID: 33750213 (opens in a new tab)

Measuring the success of blinding in placebo-controlled trials: Should we be so quick to dismiss it? (opens in a new tab)

Rebecca K Webster, Felicity Bishop, Gary S Collins, Andrea W M Evers, Tammy Hoffmann, J André Knottnerus, Sarah E Lamb, Helen Macdonald, Claire Madigan, Vitaly Napadow, Amy Price, Jonathan L Rees, Jeremy Howick

J Clin Epidemiol. 2021 Jul;135:176-181. doi: 10.1016/j.jclinepi.2021.02.022. Epub 2021 Mar 1.

DOI: 10.1016/j.jclinepi.2021.02.022 (opens in a new tab)

PMID: 33662512 (opens in a new tab)

“Consensus on Placebo and Nocebo Effects Connects Science with Practice:” Reply to “Questioning the Consensus on Placebo and Nocebo Effects” (opens in a new tab)

Andrea W M Evers, Luana Colloca, Charlotte Blease, Jens Gaab, Karin B Jensen, Lauren Y Atlas, Chris J Beedie, Fabrizio Benedetti, Ulrike Bingel, Christian Büchel, Jet Bussemaker, Ben Colagiuri, Alia J Crum, Damien G Finniss, Andrew L Geers, Jeremy Howick, Regine Klinger, Stefanie Helena Meeuwis, Karin Meissner, Vitaly Napadow, Keith J Petrie, Winfried Rief, Ionica Smeets, Tor D Wager, Vishvarani Wanigasekera, Lene Vase, John M Kelley, Irving Kirsch, on behalf of the Consortium of Placebo Experts

Psychother Psychosom. 2021;90(3):213-214. doi: 10.1159/000514435. Epub 2021 Feb 25.

DOI: 10.1159/000514435 (opens in a new tab)

PMID: 33631769 (opens in a new tab)

Thalamic neurometabolite alterations in patients with knee osteoarthritis before and after total knee replacement (opens in a new tab)

Akila Weerasekera, Erin Morrissey, Minhae Kim, Atreyi Saha, Yang Lin, Zeynab Alshelh, Angel Torrado-Carvajal, Daniel Albrecht, Oluwaseun Akeju, Young-Min Kwon, Hany Bedair, Antonia F Chen, Vitaly Napadow, Kristin Schreiber, Eva-Maria Ratai, Robert R Edwards, Marco L Loggia

Pain. 2021 Jul 1;162(7):2014-2023. doi: 10.1097/j.pain.0000000000002198.

DOI: 10.1097/j.pain.0000000000002198 (opens in a new tab)

PMID: 33470749 (opens in a new tab)

Increased Salience Network Connectivity Following Manual Therapy is Associated with Reduced Pain in Chronic Low Back Pain Patients (opens in a new tab)

Kylie Isenburg, Ishtiaq Mawla, Marco L Loggia, Dan-Mikael Ellingsen, Ekaterina Protsenko, Matthew H Kowalski, David Swensen, Deanna O'Dwyer-Swensen, Robert R Edwards, Vitaly Napadow, Norman Kettner

J Pain. 2021 May;22(5):545-555. doi: 10.1016/j.jpain.2020.11.007. Epub 2020 Dec 13.

DOI: 10.1016/j.jpain.2020.11.007 (opens in a new tab)

PMID: 33321196 (opens in a new tab)

Greater Somatosensory Afference With Acupuncture Increases Primary Somatosensory Connectivity and Alleviates Fibromyalgia Pain via Insular γ-Aminobutyric Acid: A Randomized Neuroimaging Trial (opens in a new tab)

Ishtiaq Mawla, Eric Ichesco, Helge J Zöllner, Richard A E Edden, Thomas Chenevert, Henry Buchtel, Meagan D Bretz, Heather Sloan, Chelsea M Kaplan, Steven E Harte, George A Mashour, Daniel J Clauw, Vitaly Napadow, Richard E Harris

Arthritis Rheumatol. 2021 Jul;73(7):1318-1328. doi: 10.1002/art.41620. Epub 2021 May 31.

DOI: 10.1002/art.41620 (opens in a new tab)

PMID: 33314799 (opens in a new tab)

A picture is worth a thousand words: linking fibromyalgia pain widespreadness from digital pain drawings with pain catastrophizing and brain cross-network connectivity (opens in a new tab)

Dan-Mikael Ellingsen, Florian Beissner, Tawfik Moher Alsady, Asimina Lazaridou, Myrella Paschali, Michael Berry, Laura Isaro, Arvina Grahl, Jeungchan Lee, Ajay D Wasan, Robert R Edwards, Vitaly Napadow

Pain. 2021 May 1;162(5):1352-1363. doi: 10.1097/j.pain.0000000000002134.

DOI: 10.1097/j.pain.0000000000002134 (opens in a new tab)

PMID: 33230008 (opens in a new tab)

What Should Clinicians Tell Patients about Placebo and Nocebo Effects? Practical Considerations Based on Expert Consensus (opens in a new tab)

Andrea W M Evers, Luana Colloca, Charlotte Blease, Jens Gaab, Karin B Jensen, Lauren Y Atlas, Chris J Beedie, Fabrizio Benedetti, Ulrike Bingel, Christian Büchel, Jet Bussemaker, Ben Colagiuri, Alia J Crum, Damien G Finniss, Andrew L Geers, Jeremy Howick, Regine Klinger, Stefanie H Meeuwis, Karin Meissner, Vitaly Napadow, Keith J Petrie, Winfried Rief, Ionica Smeets, Tor D Wager, Vishvarani Wanigasekera, Lene Vase, John M Kelley, Irving Kirsch, Consortium of Placebo Experts

Psychother Psychosom. 2021;90(1):49-56. doi: 10.1159/000510738. Epub 2020 Oct 19.

DOI: 10.1159/000510738 (opens in a new tab)

PMID: 33075796 (opens in a new tab)

2020

Dynamic brain-to-brain concordance and behavioral mirroring as a mechanism of the patient-clinician interaction (opens in a new tab)

Dan-Mikael Ellingsen, Kylie Isenburg, Changjin Jung, Jeungchan Lee, Jessica Gerber, Ishtiaq Mawla, Roberta Sclocco, Karin B Jensen, Robert R Edwards, John M Kelley, Irving Kirsch, Ted J Kaptchuk, Vitaly Napadow

Sci Adv. 2020 Oct 21;6(43):eabc1304. doi: 10.1126/sciadv.abc1304. Print 2020 Oct.

DOI: 10.1126/sciadv.abc1304 (opens in a new tab)

PMID: 33087365 (opens in a new tab)

TIDieR-Placebo: A guide and checklist for reporting placebo and sham controls (opens in a new tab)

Jeremy Howick, Rebecca K Webster, Jonathan L Rees, Richard Turner, Helen Macdonald, Amy Price, Andrea W M Evers, Felicity Bishop, Gary S Collins, Klara Bokelmann, Sally Hopewell, André Knottnerus, Sarah Lamb, Claire Madigan, Vitaly Napadow, Andrew N Papanikitas, Tammy Hoffmann

PLoS Med. 2020 Sep 21;17(9):e1003294. doi: 10.1371/journal.pmed.1003294. eCollection 2020 Sep.

DOI: 10.1371/journal.pmed.1003294 (opens in a new tab)

PMID: 32956344 (opens in a new tab)

Author Correction: Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain (opens in a new tab)

Yiheng Tu, Zening Fu, Cuiping Mao, Maryam Falahpour, Randy L Gollub, Joel Park, Georgia Wilson, Vitaly Napadow, Jessica Gerber, Suk-Tak Chan, Robert R Edwards, Ted J Kaptchuk, Thomas Liu, Vince Calhoun, Bruce Rosen, Jian Kong

Nat Commun. 2020 Aug 25;11(1):4347. doi: 10.1038/s41467-020-18191-4.

DOI: 10.1038/s41467-020-18191-4 (opens in a new tab)

PMID: 32843661 (opens in a new tab)

Neural activations during self-related processing in patients with chronic pain and effects of a brief self-compassion training – A pilot study (opens in a new tab)

Jacqueline Lutz, Michael P Berry, Vitaly Napadow, Christopher Germer, Susan Pollak, Paula Gardiner, Robert R Edwards, Gaelle Desbordes, Zev Schuman-Olivier

Psychiatry Res Neuroimaging. 2020 Oct 30;304:111155. doi: 10.1016/j.pscychresns.2020.111155. Epub 2020 Jul 30.

DOI: 10.1016/j.pscychresns.2020.111155 (opens in a new tab)

PMID: 32799058 (opens in a new tab)

Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain (opens in a new tab)

Yiheng Tu, Zening Fu, Cuiping Mao, Maryam Falahpour, Randy L Gollub, Joel Park, Georgia Wilson, Vitaly Napadow, Jessica Gerber, Suk-Tak Chan, Robert R Edwards, Ted J Kaptchuk, Thomas Liu, Vince Calhoun, Bruce Rosen, Jian Kong

Nat Commun. 2020 Aug 7;11(1):3948. doi: 10.1038/s41467-020-17788-z.

DOI: 10.1038/s41467-020-17788-z (opens in a new tab)

PMID: 32769984 (opens in a new tab)

Acupuncture Treatment Modulates the Connectivity of Key Regions of the Descending Pain Modulation and Reward Systems in Patients with Chronic Low Back Pain (opens in a new tab)

Siyi Yu, Ana Ortiz, Randy L Gollub, Georgia Wilson, Jessica Gerber, Joel Park, Yiting Huang, Wei Shen, Suk-Tak Chan, Ajay D Wasan, Robert R Edwards, Vitaly Napadow, Ted J Kaptchuk, Bruce Rosen, Jian Kong

J Clin Med. 2020 Jun 3;9(6):1719. doi: 10.3390/jcm9061719.

DOI: 10.3390/jcm9061719 (opens in a new tab)

PMID: 32503194 (opens in a new tab)

Impaired mesocorticolimbic connectivity underlies increased pain sensitivity in chronic low back pain (opens in a new tab)

Siyi Yu, Wen Li, Wei Shen, Robert R Edwards, Randy L Gollub, Georgia Wilson, Joel Park, Ana Ortiz, Jin Cao, Jessica Gerber, Ishtiaq Mawla, Suk-Tak Chan, Jeungchan Lee, Ajay D Wasan, Vitaly Napadow, Ted J Kaptchuk, Bruce Rosen, Jian Kong

Neuroimage. 2020 Sep;218:116969. doi: 10.1016/j.neuroimage.2020.116969. Epub 2020 May 18.

DOI: 10.1016/j.neuroimage.2020.116969 (opens in a new tab)

PMID: 32439536 (opens in a new tab)

Reduced tactile acuity in chronic low back pain is linked with structural neuroplasticity in primary somatosensory cortex and is modulated by acupuncture therapy (opens in a new tab)

Hyungjun Kim, Ishtiaq Mawla, Jeungchan Lee, Jessica Gerber, Kathryn Walker, Jieun Kim, Ana Ortiz, Suk-Tak Chan, Marco L Loggia, Ajay D Wasan, Robert R Edwards, Jian Kong, Ted J Kaptchuk, Randy L Gollub, Bruce R Rosen, Vitaly Napadow

Neuroimage. 2020 Aug 15;217:116899. doi: 10.1016/j.neuroimage.2020.116899. Epub 2020 May 5.

DOI: 10.1016/j.neuroimage.2020.116899 (opens in a new tab)

PMID: 32380138 (opens in a new tab)

Extra-Axial Inflammatory Signal in Parameninges in Migraine with Visual Aura (opens in a new tab)

Nouchine Hadjikhani, Daniel S Albrecht, Caterina Mainero, Eri Ichijo, Noreen Ward, Cristina Granziera, Nicole R Zürcher, Oluwaseun Akeju, Guillaume Bonnier, Julie Price, Jacob M Hooker, Vitaly Napadow, Matthias Nahrendorf, Marco L Loggia, Michael A Moskowitz

Ann Neurol. 2020 Jun;87(6):939-949. doi: 10.1002/ana.25731. Epub 2020 Apr 22.

DOI: 10.1002/ana.25731 (opens in a new tab)

PMID: 32239542 (opens in a new tab)

Striatal hypofunction as a neural correlate of mood alterations in chronic pain patients (opens in a new tab)

Minhae Kim, Ishtiaq Mawla, Daniel S Albrecht, Roee Admon, Angel Torrado-Carvajal, Courtney Bergan, Ekaterina Protsenko, Poornima Kumar, Robert R Edwards, Atreyi Saha, Vitaly Napadow, Diego A Pizzagalli, Marco L Loggia

Neuroimage. 2020 May 1;211:116656. doi: 10.1016/j.neuroimage.2020.116656. Epub 2020 Feb 15.

DOI: 10.1016/j.neuroimage.2020.116656 (opens in a new tab)

PMID: 32068162 (opens in a new tab)

Corrigendum to “Multivariate resting-state functional connectivity predicts responses to real and sham acupuncture treatment in chronic low back pain” [Neuroimage Clinical 23 (2019) 101885] (opens in a new tab)

Yiheng Tu, Ana Ortiz, Randy L Gollub, Jin Cao, Jessica Gerber, Courtney Lang, Joel Park, Georgia Wilson, Wei Shen, Suk-Tak Chan, Ajay D Wasan, Robert R Edwards, Vitaly Napadow, Ted J Kaptchuk, Bruce Rosen, Jian Kong

Neuroimage Clin. 2020;25:102093. doi: 10.1016/j.nicl.2019.102093. Epub 2019 Dec 12.

DOI: 10.1016/j.nicl.2019.102093 (opens in a new tab)

PMID: 31839331 (opens in a new tab)

2019

Corrigendum to ‘Multivariate resting-state functional connectivity predicts responses to real and sham acupuncture treatment in chronic low back pain’ Neuroimage Clinical, 23, 2019, 101885 (opens in a new tab)

Yiheng Tu, Ana Ortiz, Randy L Gollub, Jin Cao, Jessica Gerber, Courtney Lang, Joel Park, Georgia Wilson, Wei Shen, Suk-Tak Chan, Ajay D Wasan, Robert R Edwards, Vitaly Napadow, Ted J Kaptchuk, Bruce Rosen, Jian Kong

Neuroimage Clin. 2019;24:102105. doi: 10.1016/j.nicl.2019.102105. Epub 2019 Nov 29.

DOI: 10.1016/j.nicl.2019.102105 (opens in a new tab)

PMID: 31791913 (opens in a new tab)

Inadequate description of placebo and sham controls in a systematic review of recent trials (opens in a new tab)

Rebecca K Webster, Jeremy Howick, Tammy Hoffmann, Helen Macdonald, Gary S Collins, Jonathan L Rees, Vitaly Napadow, Claire Madigan, Amy Price, Sarah E Lamb, Felicity L Bishop, Klara Bokelmann, Andrew Papanikitas, Nia Roberts, Andrea W M Evers

Eur J Clin Invest. 2019 Nov;49(11):e13169. doi: 10.1111/eci.13169. Epub 2019 Sep 30.

DOI: 10.1111/eci.13169 (opens in a new tab)

PMID: 31519047 (opens in a new tab)

Multivariate resting-state functional connectivity predicts responses to real and sham acupuncture treatment in chronic low back pain (opens in a new tab)

Yiheng Tu, Ana Ortiz, Randy L Gollub, Jin Cao, Jessica Gerber, Courtney Lang, Joel Park, Georgia Wilson, Wei Shen, Suk-Tak Chan, Ajay D Wasan, Robert R Edwards, Vitaly Napadow, Ted J Kaptchuk, Bruce Rosen, Jian Kong

Neuroimage Clin. 2019;23:101885. doi: 10.1016/j.nicl.2019.101885. Epub 2019 May 28.

DOI: 10.1016/j.nicl.2019.101885 (opens in a new tab)

PMID: 31176295 (opens in a new tab)

Abnormal medial prefrontal cortex functional connectivity and its association with clinical symptoms in chronic low back pain (opens in a new tab)

Yiheng Tu, Minyoung Jung, Randy L Gollub, Vitaly Napadow, Jessica Gerber, Ana Ortiz, Courtney Lang, Ishtiaq Mawla, Wei Shen, Suk-Tak Chan, Ajay D Wasan, Robert R Edwards, Ted J Kaptchuk, Bruce Rosen, Jian Kong

Pain. 2019 Jun;160(6):1308-1318. doi: 10.1097/j.pain.0000000000001507.

DOI: 10.1097/j.pain.0000000000001507 (opens in a new tab)

PMID: 31107712 (opens in a new tab)

Identifying brain regions associated with the neuropathology of chronic low back pain: a resting-state amplitude of low-frequency fluctuation study (opens in a new tab)

Binlong Zhang, Minyoung Jung, Yiheng Tu, Randy Gollub, Courtney Lang, Ana Ortiz, Joel Park, Georgia Wilson, Jessica Gerber, Ishtiaq Mawla, Suk-Tak Chan, Ajay Wasan, Robert Edwards, Jeungchan Lee, Vitaly Napadow, Ted Kaptchuk, Bruce Rosen, Jian Kong

Br J Anaesth. 2019 Aug;123(2):e303-e311. doi: 10.1016/j.bja.2019.02.021. Epub 2019 Apr 1.

DOI: 10.1016/j.bja.2019.02.021 (opens in a new tab)

PMID: 30948036 (opens in a new tab)

Visual network alterations in brain functional connectivity in chronic low back pain: A resting state functional connectivity and machine learning study (opens in a new tab)

Wei Shen, Yiheng Tu, Randy L Gollub, Ana Ortiz, Vitaly Napadow, Siyi Yu, Georgia Wilson, Joel Park, Courtney Lang, Minyoung Jung, Jessica Gerber, Ishtiaq Mawla, Suk-Tak Chan, Ajay D Wasan, Robert R Edwards, Ted Kaptchuk, Shasha Li, Bruce Rosen, Jian Kong

Neuroimage Clin. 2019;22:101775. doi: 10.1016/j.nicl.2019.101775. Epub 2019 Mar 14.

DOI: 10.1016/j.nicl.2019.101775 (opens in a new tab)

PMID: 30927604 (opens in a new tab)

Somatotopically specific primary somatosensory connectivity to salience and default mode networks encodes clinical pain (opens in a new tab)

Jieun Kim, Ishtiaq Mawla, Jian Kong, Jeungchan Lee, Jessica Gerber, Ana Ortiz, Hyungjun Kim, Suk-Tak Chan, Marco L Loggia, Ajay D Wasan, Robert R Edwards, Randy L Gollub, Bruce R Rosen, Vitaly Napadow

Pain. 2019 Jul;160(7):1594-1605. doi: 10.1097/j.pain.0000000000001541.

DOI: 10.1097/j.pain.0000000000001541 (opens in a new tab)

PMID: 30839429 (opens in a new tab)

The influence of respiration on brainstem and cardiovagal response to auricular vagus nerve stimulation: A multimodal ultrahigh-field (7T) fMRI study (opens in a new tab)

Roberta Sclocco, Ronald G Garcia, Norman W Kettner, Kylie Isenburg, Harrison P Fisher, Catherine S Hubbard, Ilknur Ay, Jonathan R Polimeni, Jill Goldstein, Nikos Makris, Nicola Toschi, Riccardo Barbieri, Vitaly Napadow

Brain Stimul. 2019 Jul-Aug;12(4):911-921. doi: 10.1016/j.brs.2019.02.003. Epub 2019 Feb 10.

DOI: 10.1016/j.brs.2019.02.003 (opens in a new tab)

PMID: 30803865 (opens in a new tab)

Machine learning-based prediction of clinical pain using multimodal neuroimaging and autonomic metrics (opens in a new tab)

Jeungchan Lee, Ishtiaq Mawla, Jieun Kim, Marco L Loggia, Ana Ortiz, Changjin Jung, Suk-Tak Chan, Jessica Gerber, Vincent J Schmithorst, Robert R Edwards, Ajay D Wasan, Chantal Berna, Jian Kong, Ted J Kaptchuk, Randy L Gollub, Bruce R Rosen, Vitaly Napadow

Pain. 2019 Mar;160(3):550-560. doi: 10.1097/j.pain.0000000000001417.

DOI: 10.1097/j.pain.0000000000001417 (opens in a new tab)

PMID: 30540621 (opens in a new tab)

Brain glial activation in fibromyalgia – A multi-site positron emission tomography investigation (opens in a new tab)

Daniel S Albrecht, Anton Forsberg, Angelica Sandström, Courtney Bergan, Diana Kadetoff, Ekaterina Protsenko, Jon Lampa, Yvonne C Lee, Caroline Olgart Höglund, Ciprian Catana, Simon Cervenka, Oluwaseun Akeju, Mats Lekander, George Cohen, Christer Halldin, Norman Taylor, Minhae Kim, Jacob M Hooker, Robert R Edwards, Vitaly Napadow, Eva Kosek, Marco L Loggia

Brain Behav Immun. 2019 Jan;75:72-83. doi: 10.1016/j.bbi.2018.09.018. Epub 2018 Sep 14.

DOI: 10.1016/j.bbi.2018.09.018 (opens in a new tab)

PMID: 30223011 (opens in a new tab)

2018

Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus (opens in a new tab)

Andrea W M Evers, Luana Colloca, Charlotte Blease, Marco Annoni, Lauren Y Atlas, Fabrizio Benedetti, Ulrike Bingel, Christian Büchel, Claudia Carvalho, Ben Colagiuri, Alia J Crum, Paul Enck, Jens Gaab, Andrew L Geers, Jeremy Howick, Karin B Jensen, Irving Kirsch, Karin Meissner, Vitaly Napadow, Kaya J Peerdeman, Amir Raz, Winfried Rief, Lene Vase, Tor D Wager, Bruce E Wampold, Katja Weimer, Katja Wiech, Ted J Kaptchuk, Regine Klinger, John M Kelley

Psychother Psychosom. 2018;87(4):204-210. doi: 10.1159/000490354. Epub 2018 Jun 12.

DOI: 10.1159/000490354 (opens in a new tab)

PMID: 29895014 (opens in a new tab)

Encoding of Self-Referential Pain Catastrophizing in the Posterior Cingulate Cortex in Fibromyalgia (opens in a new tab)

Jeungchan Lee, Ekaterina Protsenko, Asimina Lazaridou, Olivia Franceschelli, Dan-Mikael Ellingsen, Ishtiaq Mawla, Kylie Isenburg, Michael P Berry, Laura Galenkamp, Marco L Loggia, Ajay D Wasan, Robert R Edwards, Vitaly Napadow

Arthritis Rheumatol. 2018 Aug;70(8):1308-1318. doi: 10.1002/art.40507. Epub 2018 Jun 22.

DOI: 10.1002/art.40507 (opens in a new tab)

PMID: 29579370 (opens in a new tab)

2017

The National Cancer Institute’s Conference on Acupuncture for Symptom Management in Oncology: State of the Science, Evidence, and Research Gaps (opens in a new tab)

Farah Z Zia, Oluwadamilola Olaku, Ting Bao, Ann Berger, Gary Deng, Arthur Yin Fan, Mary K Garcia, Patricia M Herman, Ted J Kaptchuk, Elena J Ladas, Helene M Langevin, Lixing Lao, Weidong Lu, Vitaly Napadow, Richard C Niemtzow, Andrew J Vickers, Xin Shelley Wang, Claudia M Witt, Jun J Mao

J Natl Cancer Inst Monogr. 2017 Nov 1;2017(52):lgx005. doi: 10.1093/jncimonographs/lgx005.

DOI: 10.1093/jncimonographs/lgx005 (opens in a new tab)

PMID: 29140486 (opens in a new tab)

Influence of the patient-practitioner interaction context on acupuncture outcomes in functional dyspepsia: study protocol for a multicenter randomized controlled trial (opens in a new tab)

Seok-Jae Ko, Jae-Woo Park, Jungtae Leem, Ted J Kaptchuk, Vitaly Napadow, Braden Kuo, Jessica Gerber, Laurie Dimisko, Inkwon Yeo, Junhee Lee, Jinsung Kim

BMC Complement Altern Med. 2017 Jul 14;17(1):363. doi: 10.1186/s12906-017-1869-y.

DOI: 10.1186/s12906-017-1869-y (opens in a new tab)

PMID: 28709452 (opens in a new tab)

2016

Difficulties Choosing Control Points in Acupuncture Research. Response: Commentary: Differential Cerebral Response, Measured with Both an EEG and fMRI, to Somatosensory Stimulation of a Single Acupuncture Point vs. Two Non-Acupuncture Points (opens in a new tab)

Till Nierhaus, Daniel Pach, Wenjing Huang, Xiangyu Long, Vitaly Napadow, Stephanie Roll, Fanrong Liang, Burkhard Pleger, Arno Villringer, Claudia M Witt

Front Hum Neurosci. 2016 Aug 11;10:404. doi: 10.3389/fnhum.2016.00404. eCollection 2016.

DOI: 10.3389/fnhum.2016.00404 (opens in a new tab)

PMID: 27562659 (opens in a new tab)

Neuroimaging brainstem circuitry supporting cardiovagal response to pain: a combined heart rate variability/ultrahigh-field (7 T) functional magnetic resonance imaging study (opens in a new tab)

Roberta Sclocco, Florian Beissner, Gaelle Desbordes, Jonathan R Polimeni, Lawrence L Wald, Norman W Kettner, Jieun Kim, Ronald G Garcia, Ville Renvall, Anna M Bianchi, Sergio Cerutti, Vitaly Napadow, Riccardo Barbieri

Philos Trans A Math Phys Eng Sci. 2016 May 13;374(2067):20150189. doi: 10.1098/rsta.2015.0189.

DOI: 10.1098/rsta.2015.0189 (opens in a new tab)

PMID: 27044996 (opens in a new tab)

Primary somatosensory/motor cortical thickness distinguishes paresthesia-dominant from pain-dominant carpal tunnel syndrome (opens in a new tab)

Yumi Maeda, Norman Kettner, Jieun Kim, Hyungjun Kim, Stephen Cina, Cristina Malatesta, Jessica Gerber, Claire McManus, Alexandra Libby, Pia Mezzacappa, Ishtiaq Mawla, Leslie R Morse, Joseph Audette, Vitaly Napadow

Pain. 2016 May;157(5):1085-1093. doi: 10.1097/j.pain.0000000000000486.

DOI: 10.1097/j.pain.0000000000000486 (opens in a new tab)

PMID: 26761384 (opens in a new tab)

Unanticipated Insights into Biomedicine from the Study of Acupuncture (opens in a new tab)

Hugh MacPherson, Richard Hammerschlag, Remy R Coeytaux, Robert T Davis, Richard E Harris, Jiang-Ti Kong, Helene M Langevin, Lixing Lao, Ryan J Milley, Vitaly Napadow, Rosa N Schnyer, Elisabet Stener-Victorin, Claudia M Witt, Peter M Wayne

J Altern Complement Med. 2016 Feb;22(2):101-7. doi: 10.1089/acm.2015.0184. Epub 2016 Jan 8.

DOI: 10.1089/acm.2015.0184 (opens in a new tab)

PMID: 26745452 (opens in a new tab)

2015

Manual and electrical needle stimulation in acupuncture research: pitfalls and challenges of heterogeneity (opens in a new tab)

Helene M Langevin, Rosa Schnyer, Hugh MacPherson, Robert Davis, Richard E Harris, Vitaly Napadow, Peter M Wayne, Ryan J Milley, Lixing Lao, Elisabet Stener-Victorin, Jiang-Ti Kong, Richard Hammerschlag, Executive Board of the Society for Acupuncture Research

J Altern Complement Med. 2015 Mar;21(3):113-28. doi: 10.1089/acm.2014.0186. Epub 2015 Feb 24.

DOI: 10.1089/acm.2014.0186 (opens in a new tab)

PMID: 25710206 (opens in a new tab)

The somatosensory link in fibromyalgia: functional connectivity of the primary somatosensory cortex is altered by sustained pain and is associated with clinical/autonomic dysfunction (opens in a new tab)

Jieun Kim, Marco L Loggia, Christine M Cahalan, Richard E Harris, Florian Beissner, Ronald G Garcia, Hyungjun Kim, Ajay D Wasan, Robert R Edwards, Vitaly Napadow

Arthritis Rheumatol. 2015 May;67(5):1395-1405. doi: 10.1002/art.39043.

DOI: 10.1002/art.39043 (opens in a new tab)

PMID: 25622796 (opens in a new tab)

Evidence for brain glial activation in chronic pain patients (opens in a new tab)

Marco L Loggia, Daniel B Chonde, Oluwaseun Akeju, Grae Arabasz, Ciprian Catana, Robert R Edwards, Elena Hill, Shirley Hsu, David Izquierdo-Garcia, Ru-Rong Ji, Misha Riley, Ajay D Wasan, Nicole R Zürcher, Daniel S Albrecht, Mark G Vangel, Bruce R Rosen, Vitaly Napadow, Jacob M Hooker

Brain. 2015 Mar;138(Pt 3):604-15. doi: 10.1093/brain/awu377. Epub 2015 Jan 12.

DOI: 10.1093/brain/awu377 (opens in a new tab)

PMID: 25582579 (opens in a new tab)

2014

Disruption of thalamic functional connectivity is a neural correlate of dexmedetomidine-induced unconsciousness (opens in a new tab)

Oluwaseun Akeju, Marco L Loggia, Ciprian Catana, Kara J Pavone, Rafael Vazquez, James Rhee, Violeta Contreras Ramirez, Daniel B Chonde, David Izquierdo-Garcia, Grae Arabasz, Shirley Hsu, Kathleen Habeeb, Jacob M Hooker, Vitaly Napadow, Emery N Brown, Patrick L Purdon

Elife. 2014 Nov 28;3:e04499. doi: 10.7554/eLife.04499.

DOI: 10.7554/eLife.04499 (opens in a new tab)

PMID: 25432022 (opens in a new tab)

Functional deficits in carpal tunnel syndrome reflect reorganization of primary somatosensory cortex (opens in a new tab)

Yumi Maeda, Norman Kettner, Jameson Holden, Jeungchan Lee, Jieun Kim, Stephen Cina, Cristina Malatesta, Jessica Gerber, Claire McManus, Jaehyun Im, Alexandra Libby, Pia Mezzacappa, Leslie R Morse, Kyungmo Park, Joseph Audette, Mark Tommerdahl, Vitaly Napadow

Brain. 2014 Jun;137(Pt 6):1741-52. doi: 10.1093/brain/awu096. Epub 2014 Apr 16.

DOI: 10.1093/brain/awu096 (opens in a new tab)

PMID: 24740988 (opens in a new tab)

2013

Acupuncture Evoked Response in Contralateral Somatosensory Cortex Reflects Peripheral Nerve Pathology of Carpal Tunnel Syndrome (opens in a new tab)

Yumi Maeda, Norman Kettner, Jeungchan Lee, Jieun Kim, Stephen Cina, Cristina Malatesta, Jessica Gerber, Claire McManus, Jaehyun Im, Alexandra Libby, Pia Mezzacappa, Leslie R Morse, Kyungmo Park, Joseph Audette, Vitaly Napadow

Med Acupunct. 2013 Aug;25(4):275-284. doi: 10.1089/acu.2013.0964.

DOI: 10.1089/acu.2013.0964 (opens in a new tab)

PMID: 24761177 (opens in a new tab)

Acupuncture-evoked response in somatosensory and prefrontal cortices predicts immediate pain reduction in carpal tunnel syndrome (opens in a new tab)

Yumi Maeda, Norman Kettner, Jeungchan Lee, Jieun Kim, Stephen Cina, Cristina Malatesta, Jessica Gerber, Claire McManus, Jaehyun Im, Alexandra Libby, Pia Mezzacappa, Leslie R Morse, Kyungmo Park, Joseph Audette, Vitaly Napadow

Evid Based Complement Alternat Med. 2013;2013:795906. doi: 10.1155/2013/795906. Epub 2013 Jun 17.

DOI: 10.1155/2013/795906 (opens in a new tab)

PMID: 23843881 (opens in a new tab)

2012

Acupuncture compared with oral antihistamine for type I hypersensitivity itch and skin response in adults with atopic dermatitis: a patient- and examiner-blinded, randomized, placebo-controlled, crossover trial (opens in a new tab)

F Pfab, M-T Kirchner, J Huss-Marp, T Schuster, P C Schalock, J Fuqin, G I Athanasiadis, H Behrendt, J Ring, U Darsow, V Napadow

Allergy. 2012 Apr;67(4):566-73. doi: 10.1111/j.1398-9995.2012.02789.x. Epub 2012 Feb 8.

DOI: 10.1111/j.1398-9995.2012.02789.x (opens in a new tab)

PMID: 22313287 (opens in a new tab)

2011

2010

2009

2008

2007

2006

2005

2004

2002

2001

1999

1997

1993

1992

1990